• 2023 – 2025: Postdoctoral researcher, Vectorization of drugs for cancer therapy

IC2MP, University of Poitiers, research advisor: Prof. Sebastien Papot.

Design, synthesis and characterization of prodrugs for the treatment of glioblastoma and hepatoblastoma : vectorization of actives substances.

• 2022 – 2023: Postdoctoral researcher, Nucleic acid nanotherapeutics in oncology

ChemBioPharm group – ARNA, University of Bordeaux, research advisor: Prof. Philippe Barthelemy.

Lipid antisense oligonucleotide nanoparticles (RNA-LNP). Development of a theranostic agent for the treatment of castration-resistant prostate cancer. Therapeutic, targeting and diagnostic.

• 2018 – 2021: PhD in Organic chemistry, Formulation and Biology

ChemBioPharm group – ARNA, Physiopathologie des syndromes parkinsoniens group – IMN, University of Bordeaux, research advisor: Prof. Philippe Barthelemy, Dr. Benjamin Dehay.

Pluridisciplinary research involving chemistry, formulation and biology. Synthesis and formulation of nucleolipids into lipid and polymer-based nanoparticles for Parkinson’s disease treatment.

• 2018 – 2022: Teaching assistant (120hrs)

University of Bordeaux, Pharmaceutical sciences and Biology Departments, (Fr.)

Synthesis of biomolecules, biomedical chemistry, physical chemistry, formulation

Levels: Bachelor in life sciences (1st and 3rd years), Master (1st year) in biochemistry and molecular biology, Bachelor in technology for health (TecSan, 2nd and 3rd years).

Chemistry
Multi-step organic synthesis, click chemistry, microwave assisted synthesis, phosphoramidite chemistry, solid phase nucleic acid synthesis. Purification techniques: chromatography, distillation, recrystallization, precipitation, HPLC.

Formulation
Nanoemulsions, liposomes, lipid and solid lipid nanoparticles (RNA-LNP, SLN), polymeric nanoparticles (PLGA). Self-assembling nano-systems. Techniques: rapid mixing, nanoprecipitation, microfluidic, extrusion.

Physicochemistry
Spectroscopy: UV-Visible, InfraRed, NMR (1H, 13C, 1H-1H, 1H-13C), mass spectroscopy. Dynamic light scattering (DLS), zeta potential. Differential scanning calorimetry . Chromatography HPLC. Rheology of soft matter.

Biology
In-vitro: cell culture, immunofluorescence, western blot, transfection; Epifluorescence Microscopy; Animal experimentation training (rodents), designer level

Computer science
Chemistry (ChemDraw, Marvin Sketch)
Physicochemistry (Mestrenova, Topspin, Spectra manager, Zetasizer Malvern, StarE Mettler Toledo) Office, GraphPad Prism, ImageJ Fiji, Gimp / Bibliographie (SCOPUS, PubMed, SCI Finder, Mendeley)