MONDON Martine

Pesquisador CNRS

Tópicos de Pesquisa

Síntese de ácido nucleósido pró-fármacos sensíveis

Síntese de iminoaçúcares poli-hidroxilados, os inibidores de glicosidase

Palavra-chave

prodrogas, iminoaçúcares, inibidores da glicosidase, mímicos açúcares, azépanes

Principais publicações

– “Synthesis and structure of novel analogues of uridine cyclonucleoside: ZHONG Shi, Martine MONDON, Christophe LEN, Tetrahedron 2008, 64, 7828-7836.

– “Novel triazolyl derivatives for acidic release of amines” Regis Delatouche, Martine MONDON, Adrià GIL, HIT Gilles, Christian and Philippe BERTRAND BACHMANN Tetrahedron, 2011, 67, 401-407.

– “Triazolyl derivatives for acidic release of alcohols” Martine MONDON, Régis Delatouche Christian BACHMANN, Gilles HIT, LEN Christophe Philippe BERTRAND. Eur. JOC, 2011, 2111, 2119.

– “Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri-and tetrahydroxylated azepanes” Julia DESCHAMP, Martine MONDON, Shinpei Nakagawa, Atsushi Kato, S. Dominic Alonzi, Terry D. BUTTERS, Yongmin Zhang, Matthew Sollogoub, Yves Blériot. Bioorg. Med. Chem, 2012, 20, 641-649.

– “Access to Both L-and D-C-glycosides iminosugar Exploiting a ring isomerization / alkylation strategy”: Martine MONDON, Natalie Fontelle, Jerome DESIRE, Frédéric LECORNUE, GUILLARD Jerome, Jerome Marrot, Yves Blériot. Org. Lett, 2012, vol 14, 3, 870-873.

Contato

Instituto de Química e Poitiers ambientes de Materiais (IC2MP)
Edifício B27
4 rue Michel Brunet
86022 Poitiers
Tel. : +33 (0) 5 49 45 35 18
Fax: +33 (0) 5 49 45 35 01
E-mail : martine.mondon@univ-poitiers.fr

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