O artigo aparece de . T. Supuran e Sebastian Thibaudeau na capa da revista da ChemComm Julho de 2013.
O artigo é intitulado “New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors : toward a new mode of carbonic anhydrase inhibition by sulfonamides”.
Chem. Commun., 2013, 49, 5999-5999 DOI : 10.1039/C3CC90186F
Resumo: Tertiary substituted (fluorinated) benzenesulfonamides were synthesized in superacid HF/SbF5 and tested as inhibitors of human carbonic anhydrases (hCAs, EC 188.8.131.52). Strong selectivity toward tumor-associated hCA IX, without inhibiting the offtarget hCA II, was observed, pointing out to a new mechanism of action compared to classical sulfonamides